Yagiri Pharmaceutical’s executive director is irritated by the fact that she is unable to determine the whereabouts of her beloved younger brother Seiji. To locate him, she contacts Izaya Orihara, the information broker. Meanwhile, Seiji, unconcerned that he is being looked for, continues to roam the streets of Ikebukuro together with a woman with a scar on her neck. The girl, seemingly frightened by something, leads him by the hand, wanting “to go far away.” Full of love, Seiji tenderly smiles at her. This seemingly tranquil scene is broken, however, by a sudden coincidental meeting with a certain individual followed by a girl’s fading scream.